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European journal of obstetrics, gynecology, and reproductive biology

HGH Fragment 176-191: antilipogenic rather than directly lipolytic Rat adipose ex vivo assays show that HGH Fragment 176-191 exhibits antilipogenic activity but no significant direct lipolysis under typical assay conditions

Pre-clinical research has examined whether the fragments activity is mediated through a distinct adipocyte receptor or via cross-talk with established adrenergic pathways with studies using beta-adrenergic antagonists suggesting that the fragments lipolytic activity is at least partly dependent on functional adrenergic signalling in adipose tissue