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DHT-inducible DKK1 produced by balding DP cells promotes apoptosis of neighboring follicular keratinocytes in vitro, together with the higher expression of DKK1 in balding compared with the haired scalp, suggesting that DKK1 may be one of the key factors involved in the pathogenesis of AGA 41

Mechanisms of protection of retinal pigment epithelial cells from oxidant injury by humanin and other mitochondrial-derived peptides: Implications for age-related macular degeneration