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Here is why: CJC-1295 acts as a GHRH analog, telling the pituitary to produce more GH Ipamorelin is a growth hormone secretagogue that stimulates GH release through the ghrelin receptor pathway Together, they amplify GH output through two complementary mechanisms Pharmacology studies describe how GHRH analogs and growth hormonereleasing peptides act on the GH/IGF-I axis to support growth hormone output (Veldhuis et al., 2009)

Free Radical Biol Med 20:331342 van Faassen EE, Bahrami S, Feelisch M, Hogg N, Kelm M, Kim-Shapiro DB, Kozlov AV, Li H, Lundberg JO, Mason R, Nohl H, Rassaf T, Samouilov A, Slama-Schwok A, Shiva S, Vanin AV, Weitzberg E, Zweier J, Gladwin MT (2009) Nitrite as regulator of hypoxic signaling in mammalian physiology

J Diabetes Res (2015) 2015:341583