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The Numbers Multiple studies have found a strong association between FRAAs, CFD, and autism: 38% of children with ASD have confirmed CFD (based on lumbar puncture studies) 71% of children with ASD test positive for FRAAs (based on blood tests) 83% of CFD cases in children with ASD are caused by FRAAs This means that a significant subset of children with autism perhaps one-third to two-thirds have detectable FRAAs, and many of those have measurable brain folate deficiency