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Iron overload compromises preimplantation mouse embryo development

10.1016/j.psj.2024.104242 262 ZuoX.GaoL.PengX.DongL.HuangM.HuT.et al (2024)

Glutathione biosynthesis occurs in two sequential, ATP-dependent enzymatic steps that take place in the cytosol: Step 1: The enzyme glutamate-cysteine ligase (GCL) combines glutamate and cysteine to form gamma-glutamylcysteine