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The anatomical locations of these white-matter abnormalities are consistent with clinically observed impulsivity, affective reactivity, and aberrant processing of emotional stimuli (128131)

Thrombocytopenia defined as platelet count 150 k/cumm (20.3% vs 4.9%, p value 0.007)

This is particularly important given that retatrutide is still in clinical development and is not yet available as a licensed treatment through the NHS or private prescribing channels in the UK