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This is not an issue with an injection (since IM/IV bypasses the gut), but if a patient is also taking oral supplements, they should separate them from tetracycline dosing

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Liu X, Zhao T, Wang L, Yang Z, Luo C, Li M, et al

Engineering a Stabilized Analogue at Metabolic Pharmaceuticals (mid-1990s2000) The native 177 to 191 fragment was a useful demonstration but not, in its raw form, a candidate for oral drug development