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In real-world use

In a preliminary report, we discovered hemoglobin alpha-a1 (Hb-a1 mRNA and Hb protein) expression in both mouse and human T-lymphocytes, showed its differential levels in various T-lymphocyte polarized states, and elucidated its increased production in response to redox perturbations, indicating a potential antioxidant function in these cells ( + T-lymphocytes after psychological trauma, proposing irregular cellular activation in the absence of Hb-a1

Turning them loose on the world and waiting for reports of adverse events is not the same or as safe as a controlled clinical trial

Metabolic reprogramming and reactive oxygen species in T cell immunity