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HK2 kinase assays were conducted in a mixed system by adding 50 ng of purified, active human HK2 to a kinase buffer containing 5 g of purified Flag-RIPK1

Acetyl CoA and NADPH accumulated from FAO metabolism in the cytosol are needed to initiate FAS

Though he takes no salary from AngioGenex, Benezra owns nearly 9 percent of the company he helped found through stock or options, setting him up for a lucrative payday if the company is acquired or its drugs come to market

Nucleic acid aptamers are single-stranded DNA or RNA oligonucleotides capable of specifically binding to a wide range of molecules with dissociation constants from the nano- to picomolar range for protein targets and in the micromolar range for smaller molecules