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Thus, this increase in S-5-HT from before to after L-carnitine was about 8-fold in CFS and 6-fold in hypothyroidism

This could trigger a positive feedback cycle whereby protein aggregates trigger the aggregation of other proteins in a chain reaction that eventually captures elements of the proteostatic mechanisms in place to counteract them

Finding the "best" set of features to build a predictive model is a complex combinatorial problem and available methods are generally classified into two categories: filtering methods (those which rank individual features according to some criteria) and more involved wrapper algorithms, which use classification methods directly to evaluate a particular set of features

10.1016/j.foodres.2024.114082 32 LiY.LiuJ.ShiX.LiS.ZhangH.ZhangL.et al (2024d)