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However, as previously reported, some phytochemicals increase the activity of L-glutamate decarboxylase (L-GAD), an enzyme responsible for the conversion of L-glutamate to GABA, and therefore, the level of GABA increases in the brain, especially in the hippocampus which leads to the activation of inhibitory pathway and help in the control of seizure (Kandeda et al., 2021a)

For your dog, supplementation is recommended because it is generally more economical and practical than trying to feed wild sockeye salmon every day

PLoS ONE 14 , e0225931 (2019)

This protective effect can be interpreted based on two complementary suggested pathways, initially, through the direct inhibition of the NLRP3/caspase-1/GSDMD C-NT signaling pathway