dihexa potency compared to bdnf synaptogenesis Brain-Derived Neurotrophic Factor Differentially Regulates Excitatory and Inhibitory Synaptic Transmission in Hippocampal Cultures Comment "curious" for the full

Comment "curious" for the full newsletter. There's a molecule rumored to be 10 million times more powerful than BDNF for synaptogenesis, neuron growth, learning, and memory. It's called Dihexa. It's gaining Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted The physiopathology of brain derived neurotrophic factor Physiological Reviews American Physiological Society Knockdown of brain derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis Molecular Psychiatry

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