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doi:10.1146/annurev-biochem-060815-014710 53

Gene expression: GHK-Cu has been documented to up- or downregulate over 4,000 human genes in cell-culture models, affecting pathways related to inflammation, tissue repair, and antioxidant defense (PMID 29986520)

Standardized delirium assessments and sedative exposure should be accounted for

The Role of Low-Dose Naltrexone (LDN) Naltrexone, particularly in low doses (LDN), has been shown through in vitro (typically test tube-based) and ex vivo (tests on living tissues in an external environment) studies to improve TRPM3 dysfunction in NK cells