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Physical and Cognitive Effects The most consistently reported short-term effects include: Increased drowsiness and grogginess, which raises the risk of falls, accidents, and poor decisions Dizziness and unsteadiness, which the NHS lists as serious enough to warrant urgent assessment if severe Impaired coordination and slower reaction time, making driving or operating machinery especially dangerous Slowed thinking, confusion, and reduced ability to focus Nausea, which can become dangerous if sedation is also present because of aspiration risk Next-day residual impairment, even after obvious intoxication has passed Psychiatric and Emotional Effects These are often the more consequential harms

630 PL37 can increase the concentration of enkephalins peripherally and enhance the endogenous opiodergic system

It is very slightly soluble in water, insoluble in alcohol, chloroform, ether