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Edaravone (MCI-186), which targets the scavenging of oxygen free radicals to reduce ROS (Ma et al., 2022), has demonstrated safety and efficacy in stroke patients, and its efficacy and therapeutic time window were further investigated in a multicenter, prospective, randomized, and open-label study of combined thrombolytic therapy (the YAMATO study) (Aoki et al., 2017), and this drug is currently in the listing stage

The PCA analysis showed that the first two components explained 65.42% of the variance in oxidative and antioxidant biomarkers, which were largely driven by positive factor loading scores of OSI, which simply shows that A

Wang CH, Tsuji T, Wu LH, Yang CY, Huang TL, Sato M, et al

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