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Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association Pathology Outlines Melanotic macule Case of melanotic macule in a 46 F Let's review ORAL MELANOTIC MACULE FOCAL MELANOSIS . The oral melanotic macule is a flat, brown, mucosal discoloration produced by a focal increase in melanin Melanosis Coli El Atlas Gastrointestinal

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