interaction of haloacetonitriles with glutathione and glutathione-s-transferase Schematic representation the structure of a Transglutaminase 2 crosslinks the glutathione

Seventy percent of study volunteers showed collagen increases compared to untreated controls a response rate significantly higher than that achieved by either comparator compound, both of which are considered first-line clinical options for photoaged skin

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ER is not only a major site of protein synthesis and modification but also takes part in several signal transduction pathways (Cong et al., 2016) The Nrf2-Keap1 signaling system and mitochondria interact to a great extent in cell metabolism, redox homeostasis, and antioxidant defense

10.1016/j.freeradbiomed.2017.04.001 337 SecchieroP.BoscoR.CeleghiniC.ZauliG