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Although epithelium acts as a physical and antimicrobial barrier, ingested materials and enteric pathogens can promote inflammation by stimulating the production of proinflammatory cytokines, which further contribute to OS

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For example, it was added to dithranol and methotrexate in topical treatment of psoriasis Agarwal and colleagues, Javadzadeh and Hamishehkar

The key consideration is that Dihexa's effects persist beyond compound clearanceshifting protocols mid-study doesn't create an immediate reset but rather modulates ongoing neuroplastic processes already in motion