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Serum starvation can induce NP-MSCs to enter a quiescent state, which is conducive to stemness maintenance (Stolzing et al., 2006

Thurston RC, Kubzansky LD, Kawachi I, Berkman LF

This is one reason gentle handling is emphasized

in vitro seem to be rather an indirect process resulting from changes in membrane structure ( + ions, proton pumps use the ATP energy (Zhang et al., 2011