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drc.bmj.comZ Miyan, N WarisBMJ Open Diabetes Research & Care, 2020drc.bmj.com 8:1151 Hasan NU, Makki U, Abid I, Ur M, Abid Butt R Association of vitamin B12 deficiency with intake of oral metformin in diabetic patients

High dose intravenous (IV) thiamine supplementation (500 mg thiamin dissolved in 100 mL normal saline) led to a reduction in the frequency of migraine attacks (20)

This intravenous infusion bypasses the digestive system, ensuring maximum absorption and immediate availability of nutrients to support immune function