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Saliva was selected due to its non-invasive collection, 70% DNAm concordance with blood, and logistical convenience for at-home self-sampling protocols

The physician should provide information to the patient about the signs and symptoms of hepatotoxiciy that should cause alarm (e.g., nausea, fatigue, lethargy, pruritus, jaundice, right upper quadrant tenderness and "flu-like" symptoms)