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Persistent activation of DDR at telomeres is sufficient to trigger replicative senescence 27

Finally, I suggest that the proposed speed limit indicators could easily be replicated in other in other cities, enabling cross-city comparisons and facilitating the identification of leading cities in this domain, thereby providing a useful tool for research, advocacy and policy initiatives seeking to reduce urban traffic speed limits

Its thiol (-SH) group is the key functional site responsible for its wide range of biochemical activities

Muscle Nerve 69:477489 Hemerkov P, Vali M (2021) Role of oxidative stress in the pathogenesis of amyotrophic lateral sclerosis: antioxidant metalloenzymes and therapeutic strategies