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Biochim Biophys Acta (BBA) 1876(1):188556

doi:10.3390/ANTIOX12020393 Sun Y, Liu W, Zhang H, et al

At predetermined time points (2, 6, 12, and 24 h post-administration), the mice were euthanized, and the residual gel on the skin surface at the application site was removed by washing with PBS

Unlike PDT, limited by shallow light penetration, or SDT, which suffers from relatively low sonosensitizer-to-ROS conversion efficiency despite improved depth access, the RT/RDT strategy leverages X-rays exceptional tissue penetration and strong ionizing capacity