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The dysregulation of the interoceptive network mediated by neuroinflammation and central energy deficiency may be the core central mechanism by which PEM patients exhibit exaggerated perceptions of fatigue and pain after mild exertion, and this process is potentially regulated by the interaction between glial cell activation and neuronal mitochondrial dysfunction in the insular cortex

Msemburi W, Karlinsky A, Knutson V, Aleshin-Guendel S, Chatterji S, Wakefield J

However, it is critically important to remember that there is no single miracle cure or quick fix for complex neuroimmune conditions like Long COVID, ME/CFS, or dysautonomia

Whey protein hydrolysate supplementation accelerates recovery from exercise-induced muscle damage in females