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Berberine decreased fasting blood glucose by direct inhibition of gluconeogenic genes, phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase) in liver

Knockout of the lysosomal enzyme, DNase II, revealed that it plays a role in the removal of DNA fragments remaining after nuclear membrane fragmentation, but is not required for the initiation of organelle breakdown

We contend that xenotransplantation using such systems, preserving patient genetic background in an in vivo setting, may be well-suited to basic research in personalized radiotherapy

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