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5 Shift from baseline to week 104 in glycemic status

[315] Comment: A few commenters recommended stratification by ED volume, with a commenter suggesting stratifying ED volume as small, medium, or large, to enable meaningful comparisons across hospitals with varying patient volume and resource levels

Lab tests show pp 332 activation leads to suppression of lipogenic gene expression and activation of genes involved in mitochondrial biogenesis

Clinical trials measuring body composition found that fat mass reduction occurred without corresponding increases in lean tissue mass, confirming the absence of anabolic muscle-building effects