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As a control, normal RBCs (nRBC) were identically treated

i , j , Quantification of NETs in WT, XKR8 KO and PAD4 KO BMNs treated with PMA (100 nM, 6 h), A23187 (1.25 M, 4 h), LPS (10 g/mL, 2 h), and nigericin (5 M, 4 h) or co-cultured with L

Interestingly, boosting levels of NAD + through NR treatment alleviated these phenotypes by reducing senescence and systemic inflammation [117,118,119]