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3.4 Methodological quality of included reviews The methodological quality of the included reviews was assessed using the AMSTAR-2 tool (Supplementary Table 2)

Clinical observations show patients with chronic tendon complaints typically notice reduced pain within 2 to 4 weeks

To determine the effect of hypothermia on cellular uptake of CIPp-18, cells were incubated in a pre-cooled growth medium containing 2.0 M CIPp-18 for 3 h at 10 C