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Dehydrocostuslactone attenuated oxygen and glucose deprivation/reperfusion-induced PC12 cell injury through inhibition of apoptosis and autophagy by activating the PI3K/AKT/mTOR pathway

The CD (Teklad Diets 110367) was lower in fat and sucrose (3.67 kcal/g, 12.7% kcal fat, 72.4% kcal carbohydrate, 150 g/kg sucrose) with an approximately equivalent (40% / 26% / 33% SFA/MUFA/PUFA) fatty acid distribution, a moderate 9.6 -6:-3 ratio, and equivalent levels of vitamins, minerals, and protein when considered on a basis of energy density

There have been different strategies to optimize GSH yield and productivity in bacteria and yeasts by means of metabolic and evolutionary engineering, media optimization and bioprocess engineering

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