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Given its nutrient richness and biofunctional diversity, RJ is widely used as a dietary supplement and for antibacterial and anti-inflammatory treatments ( 4.6.2 Mechanism of action in dry eye disease RJ exhibits natural antioxidative characteristics, significantly reducing ROS and nitric oxide production in macrophages and boosting activities of antioxidant enzymes like SOD and glutathione ( RJs anti-inflammatory effects are mediated through its fatty acid analogs, including 10-hydroxy-2-decanoic acid, 10-hydroxy decanoic acid, and sebacic acid, which effectively inhibit the release of pro-inflammatory cytokines and other inflammatory mediators (Yang et al., 2018b)

As an example of a 2016 update, it is important to note that there have been new substances or clarifications added to the Prohibited List in various categories, including, but not limited to, meldonium (Mildronate) and insulin-mimetics, including all insulin-receptor agonists

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We first examined exophers produced by neurons co-expressing mCherry and GFP::IFD-1 to find that exophers can contain extruded GFP::IFD-1 foci in this background (Fig