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this will lead to increased lactate concentrations

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doi: 10.1128/CMR.11.3.514 163 SteingartKRDendukuriNHenryMSchillerINahidPHopewellPCet al

Other groups found similar outcomes that linked the GPx3 locus to ALS but were also able to demonstrate that lower GPx3 levels strongly correlated with more advanced disease, in addition to showing significant motor deficits in a knockdown zebra fish model 21