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In all KO genotypes, cFos induction in the AP and NTS was markedly blunted compared to WT mice, establishing that both AMY1R and AMY3R are necessary for transmitting cagrilintides central effects

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The results showed that the peptide could accelerate the healing process by the mechanism associated with accelerated granulation tissue formation, reepithelialization, dermal remodeling, and collagen deposition through ERK1/2 signaling pathway

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Retatrutide is a synthetic peptide based on a glucose-dependent insulinotropic polypeptide (GIP) backbone, but uniquely, it functions as a triple agonist

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