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doi: 10.1046/j.1365-2826.1999.00330.x 42 KamegaiJ.WakabayashiI.MiyamotoK.UntermanT

The C-terminal half of JAK proteins comprises a pseudokinase domain (PKD) followed by a kinase domain (KD), also known as JH2 and JH1, respectively (77)

In laboratory and preclinical models, these peptides have been investigated for their effects on tissue remodeling, angiogenesis, inflammatory modulation, and extracellular matrix activity