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Description

Accordingly, insulin and counter-insular signals in the liver modulate systemic glycemia primarily by regulating hepatic glucose production and utilization rather than by forcing glucose entry through high-affinity transport

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Meanwhile, in the outermost layer of the cornea, the epithelial cells possess tight junctions and efflux pumps that promote drug loss either by preventing paracellular drug permeation or inhibiting drug entry into the cell [28]

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While significant developments have been made in the field of hydrogel DDS, there are several barriers that impede the transition from research and development into clinical applications

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