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However, assessing the environmental and safety impacts of metal-doped CDs-based nanozymes is also significant

Interestingly, the bacterium Bacillus oleronius, isolated from Demodex mites infesting the HFs of rosacea patients, has been shown to stimulate an inflammatory response in the skin, thus contributing to disease flares

D.PrietoM.et al (2014)

Metformin, an AMPK activator, inhibits TGF-1-induced myofibroblast differentiation by promoting AMPK expression, leading to myofibroblast deactivation and apoptosis, reduction in the expression of type I collagen, fibronectin (FN), and -SMA in fibroblasts, and downregulation of ECM protein levels, thereby slowing or reversing PF (Rangarajan et al., 2018)