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In the absence of such data, local epidemiology and susceptibility patterns may contribute to empiric selection of therapy

The resulting model was refined in REFMAC in space group P 2 1 2 1 2 with a = 63 , b = 180 , c = 55 unit cell to 1.92 and R work/free 18.3%/21.8%, correspondently

A close association exists among stroke, ischemia-reperfusion injury and hemorrhagic stroke, as abnormalities in cerebral blood supply are a common feature for all of these conditions, which may lead to either damage or death of neural cells (9)