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Description

Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with GLP-1 receptor agonists, including semaglutide

Model: Female US NIH National Institute on Aging (NIA) Aged Rodent Colony mice aged 22 months Dosage: 10 mg/kg of 5-amino-1MQ administered with subcutaneous injections for eight weeks