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The study of Meguid et al., involved 30 healthy children and 30 children affected by autism (18 males, 12 females), aged 311 years, all diagnosed with DSM-V and CARS, with no reported medical comorbidities and in good physical health

Mande SS, Sarfaty S, Allen MD, Perham RN, Hol WG (1996) Proteinprotein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase

37 reported decreased k cat app and increased K m app (GSSCys) values upon replacement of Lys19 in a single cysteine mutant of human Grx1

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