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The estimated treatment ratios of the mean AUC 0 of cagrilintide in each of the renal impairment groups to the normal renal function group were 1.23 (90% CI, 0.911.66) for the mild renal impairment group, 1.18 (90% CI, 0.871.59) for the moderate renal impairment group and 1.21 (90% CI, 0.871.68) for the severe renal impairment group

However, we fully recognize that the concentrations of LOX-metabolites utilized in this study were much higher than those detected in plasma and mammary tissues of rats orally administered DHA

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If a vial will require more than 20 draws, consider reconstituting into a fresh sterile vial after the stopper shows visible wear