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We proposed to renumber the current paragraph (b)(4) of 425.512 to paragraph (b)(5) and revise the cross references therein to reflect this renumbering

And if a patient meets their goalsloses weight, improves blood sugar, blood pressure, or cholesterolwe may even de-escalate therapy by lowering the semaglutide dose or switching to liraglutide to prevent excess weight loss, which can come at the expense of muscle mass. Overall, switching works best when its intentional and coordinated with your physician

As mentioned, though, you should avoid drinking large amounts of water during meals to prevent overfilling your stomach

As treatment continues and things are stable, the frequency may be reduced (for example, checks every 6 months)