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Housing, handling, and experimental procedures were approved by the University of Haifa Institutional Committee for animal experiments in accordance with National Institutes of Health guidelines

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Besides SOD and APX that directly scavenge ROS, this cycle also involves other enzymes such as MDHAR, DHAR, and GR, which act as antioxidant-regenerating enzymes that regenerate GSH and ASA from their oxidized forms (Mittler, 2002