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The most common error involves vigorous shaking during reconstitution, which denatures the peptide structure and renders it inactive

Once-daily administration of CJC-1295 normalizes growth in the GHRH knockout mouse. American Journal of Physiology

There is a lack of long-term effects data, including concerns about abnormal cell growth and the need for ongoing evaluation and monitoring

Reported side effects Mild local irritation or discomfort at the injection site Headache (typically mild and short-lived) Nausea or dizziness in some patients Sweating Mild fever more commonly reported in post-stroke use, generally manageable with standard antipyretics Contraindications Cerebrolysin is not recommended for individuals with: Active epilepsy or seizure disorders Severe renal (kidney) impairment Known hypersensitivity to any component of the formulation Note: A 2023 Cochrane review noted a potentially higher rate of spontaneous adverse events in some stroke trial subgroups