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Abstract Parkinsons disease (PD) is a chronic and progressive neurodegenerative disorder characterized by a complex pathophysiology and a range of symptoms

From a clinical perspective, such metabolites may eventually complement behavioral assessments by helping to identify metabolic subgroups more likely to benefit from targeted nutritional interventions

Among the nutraceuticals most investigated as single agents, yohimbine has been used for over several decades as a therapeutic option for ED [21], being particularly successful in patients with non-organic forms [22], whereas Korean red ginseng has been suggested to improve ED, although with less firm evidence [23]