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[DOI] [PubMed] [Google Scholar] 122.Bianciotto M, Chiappini E, Raffaldi I, Gabiano C, Tovo PA, Sollai S, et al

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In the absence of MCAD, it appeared that, instead, molecular competition an intrinsic biochemical feature of the pathway topology was the cause of the pathways susceptibility to becoming overloaded and losing its capability to maintain flux at high substrate concentrations