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Bioinformatics studies have identified Yes-associated protein 1 (YAP1) as a potential key regulator of ferroptosis in VSMCs of unstable plaques

This corresponds to 1.9% of the total coding proteins in the genome, a figure comparable to that found in other species 27 (Supplementary Fig

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Taken together, hyperhomocysteinemia triggers the development and progression of PD by different mechanisms, including oxidative stress, mitochondrial dysfunction, apoptosis, and endothelial dysfunction [Fig