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7.1 Identification of gutliver axisrelated therapeutic targets The future studies to systematically identify key molecular targets involved in gutliver communication during cadmium exposure, including intestinal barrier regulators, bile acid signaling pathways, microbial metabolites, and inflammatory mediators, which may serve as potential intervention targets

Therapeutic strategies aimed at inhibiting collagen crosslinking have focused on targeting key enzymes and products such as LOX, TGase, and AGEs

doi: 10.1016/j.neurobiolaging.2019.12.013

Results We used the GSH/GSSG-Glo Assay to monitor GSH and GSSG levels and observe the oxidative stress in adherent HEK-293 cells and suspension K-562 cells dosed with menadione (Figures 3 and 4)