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doi: 10.1016/j.bbapap.2014.01.002

Those with extensive stage disease may receive other regimens such as irinotecan (Camptosar, CPT-11) with cisplatin (NCCN 2014b

The critical role of glucuronidase treatment has also been emphasized by Ali et al

Therefore, limiting Asn metabolism in tumor cells and immunosuppressive cells in the TME and protecting and promoting Asn metabolism in anti-tumor immune cells should be a problem to be solved