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Teplizumab exerts a potent affinity for the CD3 E chain, thereby impacting CD8 + T cells that participate in the autoimmune attack of pancreatic cells [42]

10.1016/j.jep.2023.117371 13 ChenK.YanM.LiY.DongZ.HuangD.LiJ.et al (2017)

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The authors also argued that the promotion of vascularization improved the efficacy of Cisplatin due to better tumour blood perfusion, which improved cytotoxic delivery, leading to tumour regression in mice model