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Flexible conformation changes, cell-penetrating peptide motifs, aromatic amino acids, and basic residues help give MSPs membrane permeability [14, 15]

[5] Typical adult anti-inflammatory dosing is 0.04-0.2 mg/kg IV or IM ( 3-15 mg for a 70 kg patient), with limited benefit above 20 mg/day outside oncologic or neurologic emergencies