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In fact, the massive LPO induced by an APAP overdose of 400 mg/kg decimated the liver and caused the death of the animal within 45 h

A pilot study published in Movement Disorders demonstrated temporary symptomatic improvement in Parkinson's disease patients following IV glutathione administration, though larger trials are needed

Spanaki C, Zaganas I, Kounoupa Z, Plaitakis A

*Correspondence: Xue Yang, [email protected] Wei, [email protected] Jiang, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Cardiovascular Metabolism, a section of the journal Frontiers in Cardiovascular Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers